The Pioneer Campus brings together the most advanced technologies in biomedicine and engineering to further accelerate Helmholtz Zentrum München's excellence in metabolism and other areas of outstanding expertise. More Details ...

With the Helmholtz Pioneer Campus, Helmholtz Zentrum München is launching a unique project to synthesize advanced engineering and cutting-edge biomedical research to impact future therapies. More Details ...

Our Philosophy

At the Helmholtz Pioneer Campus, exceptional talents from various scientific fields share their expertise to solve the most important biomedical challenges of our time. The campus creates a unique atmosphere for interdisciplinary collaboration in an ideally equipped, creative and dynamic environment, beyond hierarchies and administrative hurdles. Our commitment to highest scientific standards and unlimited enthusiasm draws upon the best and most imaginative scientists.
The Helmholtz Pioneer Campus organizational culture thrives on

  • scientific freedom and creativity
  • bold collaboration across disciplines- pursuit of serendipitous discoveries
  • accelerated translation of new discoveries for precision medicine and health
  • a global perspective on science and inspiration for future scientists

 

 

Scientific Concept

The Helmholtz Pioneer Campus is a catalyst for decisive breakthroughs in biology and medicine. Focused on bioengineering and metabolic disease mechanisms, it supports the next generation of international research leaders and encourages scientific vision. Offering top tier resources for young, up and- coming scientists, the campus catalyzes interdisciplinary teamwork towards (but not limited to)

  • new approaches for personalized medicine in prevention, diagnosis and therapy
  • novel biomarkers and biosensors for the early identification and improved monitoring of diseases
  • seamless integration of basic discovery, bio-engineering and clinical application
  • rapid translation of innovative results into IP, licensing and new ventures

 

 

Our Successes

Image courtesy of D. Razansky


V. Ntziachristos, D. Razansky - Bridging technologies:

Optoacoustic tomography combines the specificity of optical imaging with the penetration and spatiotemporal resolution of ultrasound. MSOT (multispectral opto-acoustic tomography) enables non-invasive and quantitative diagnostics, and facilitates real-time precision surgery.

 

 

Image courtesy of T. Müller


M. H. Tschöp - Breakthroughs in drug-development:

The novel, anti-obesity & anti-diabetic synthetic peptides combine the functional entities of up to three physiological hormones, a concept called ‘unimolecular polypharmacy’. Iterative cycles of medicinal chemistry, in-vivo pharmacology and functional testing require trusted partnerships across academic- and corporate partners.

Citations:
http://www.cell.com/cell-metabolism/fulltext/S1550-4131
http://www.cell.com/cell-metabolism/fulltext/S1550-4131

 

 

Image courtesy of A. Aliluev


H. Lickert, F. Theis, M. Meier – Challenging stem cell concepts:

Determining stem- and progenitor cell heterogeneity, -plasticity and mechanisms of lineage choice requires the seamless integration of state of the art genetic-, single cell -omics, computational-, 3D-mini organ- and microfluidic 'on-chip’ technologies.

Citations:
https://www.nature.com/nature/journal/v535/n7612/full/nature18624.html
https://www.nature.com/nature/journal/v535/n7611/full/nature18320.html
http://www.pnas.org/content/113/29/E4143.long

 

 

Research Focus

(1) HPC will embrace the human organoid-technology (3-dimensional, human ‘organs in a dish’) to model human physiology and disease, and reveal so far un-accessible molecular-metabolic routes for therapeutic intervention.

(2) Organoids offer unprecedented opportunities for the development and testing of new molecular probes, biosensors, synthetically engineered molecular circuits, imaging- and optical devices etc.; organoids promise to close the translational gap and complement existing in-vivo models, in particular the exceptional resources and expertise at the GMC.

(3) The synthesis of biomedical-, engineering-, bio-sensing and imaging expertise puts
HPC in a prime position to address relevant aspects of the ‘big-data’ revolution.

 

 

Contact

Prof. Dr. Matthias Tschöp
Director of Biomedicine
E-Mail
Vita

Prof. Dr. Vasilis Ntziachristos
Director of Bioengineering
E-Mail
Vita

Dr. Thomas Schwarz-Romond
Director of Operations
E-Mail
Vita