Boyan's team deciphers the genetic and epigenetic blueprints of brain development and evolution, thereby unravelling new paradigms at the interplay of transcription factors, chromatin topology and the control of gene expression in vivo.

Celia's team applies single-cell approaches to interrogate molecular features as predictor of molecular age. The assessment of intra-organ cell-to-cell variability will instruct precision diagnostics and personalized treatments.

Na Cai’s research group uses computational methods on large-scale genetic and multi-omic data to investigate the heterogenous etiology of Major Depressive Disorder (MDD) and other neuropsychiatric conditions, with particular focus on metabolic links to diseases and gene environmental interactions. 

Oliver's team combines targeted probe development and novel imaging setups to rapidly translate the technological advantages of SWIR into new imaging capabilities for both preclinical- and therapeutic applications.

Matthias' team advances the microfluidic organ-on-chip technology to characterize biomolecules and their functional interactions on the single cell level and in the context of whole organs. 

Cells accomplish the biochemical reactions of life by concentrating their proteins into a variety of subcellular compartments called organelles.  Our group explores the relationship between the form of the organelle and the function of its resident macromolecules.  How does organelle architecture direct molecular function, and reciprocally, how do macromolecules sculpt and shape organelles?

Jian’s team synthesizes novel classes of nanomaterials with unique chemical and optical properties. We aim to apply these materials towards the development of unconventional approaches to biological imaging and sensing.

Ryan’s team transforms neuroscientific breakthroughs into new technologies and assays for autonomous and autonomic system control, towards the goal of improving the quality of life and providing dignity to demographics afflicted by aging, disease and illness.