Principal Investigators
HPC Principal Investigators are outstanding scientists with a proven track record in their respective fields and the ambition to make a difference in biomedicine, harnessing engineering and informatics tools. They are interdisciplinary by nature, highly collaborative, and committed to drive a globally competitive research program.

Boyan Bonev
3D Genome & Molecular Neurobiology
Boyan's team deciphers the genetic and epigenetic blueprints of brain development and evolution, thereby unravelling new paradigms at the interplay of transcription factors, chromatin topology and the control of gene expression in vivo.

Celia P. Martinez-Jimenez
Molecular Ageing
Celia's team applies single-cell approaches to interrogate molecular features as predictor of molecular age. The assessment of intra-organ cell-to-cell variability will instruct precision diagnostics and personalized treatments.

Na Cai
Translational Genetics
Na Cai’s research group uses computational methods on large-scale genetic and multi-omic data to investigate the heterogenous etiology of Major Depressive Disorder (MDD) and other neuropsychiatric conditions, with particular focus on metabolic links to diseases and gene environmental interactions.

Oliver Bruns
Next-Generation in vivo Imaging
Oliver's team combines targeted probe development and novel imaging setups to rapidly translate the technological advantages of SWIR into new imaging capabilities for both preclinical- and therapeutic applications.

Matthias Meier
Bioengineering and Microfluidics
Matthias' team advances the microfluidic organ-on-chip technology to characterize biomolecules and their functional interactions on the single cell level and in the context of whole organs.

Benjamin Engel
Structural Cell Biology
Cells accomplish the biochemical reactions of life by concentrating their proteins into a variety of subcellular compartments called organelles. Our group explores the relationship between the form of the organelle and the function of its resident macromolecules. How does organelle architecture direct molecular function, and reciprocally, how do macromolecules sculpt and shape organelles?

Jian Cui
Nanomaterials and Nanophotonics
Jian’s team synthesizes novel classes of nanomaterials with unique chemical and optical properties. We aim to apply these materials towards the development of unconventional approaches to biological imaging and sensing.

Ryan Remedios
Autonomous and Autonomic Systems
Ryan’s team transforms neuroscientific breakthroughs into new technologies and assays for autonomous and autonomic system control, towards the goal of improving the quality of life and providing dignity to demographics afflicted by aging, disease and illness.